Yasminelle (ethinyl estradiol 20 µg + drospirenon 3 mg)
The oral contraceptive Yasminelle contains 20 μg ethinyl estradiol and 3 mg drospirenon. The daily intake is one pill in 21 days followed by a 7 day pause.
Trials, including 736 women, showed a Pearls Index of 0,31 for Yasminelle. This contraceptive effect equals the additional contraceptive on the market with a general Pearls index on 1.
The control of bleeding and additional adverse events of Yasminelle is comparable to Mercilon. Mercilon contains 20 μg ethinyl estradiol and 150 μg desogestrel and has the same oral/intake regimen.
Yasminelle is significantly more expensive than other contraceptives containing 20 μg ethinyl estradiol. Therefore, the rational requirement is to only prescribe Yasminelle to women, who can not be treated in other ways.
There is no reimbursement for Yasminelle.
Yasminelle was marketed 9 October 2006.
Institute for Rational Pharmacotherapy, 29 November 2006