IRF has previously recommended drugs containing fentanyl, which is used for treatment of cancer pain (Actiq lozenges and I
Instanyl spray) (1,2). On July 12th, 2010, the new drug Abstral (fentanyl) was marketed.
Abstral sublingual tablets are found in different strengths; 100, 200, 300, 400, 600 and 800 µg.
Abstral is not under the rules of general imbursement. You have to apply for single reimbursement or terminal reimbursement.
Abstral is cheaper than Actiq and Instanyl in equipotent dosages, but more expensive than morphine – which has to be given as an injection in order to achieve the same fast effect as Abstral.
The Institute for Rational Pharmacotherapy, September 1st, 2010.